Rat activated protein C,APC ELISA KIT

SKU: E0301Ra

Size:96 Tests-1 Kit

Background:Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization (By similarity). {ECO:0000250|UniProtKB:P25054, ECO:0000250|UniProtKB:Q61315}.

Research_area:

Applications:ELISA

Target_protein:Apc

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.157ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:activated protein C

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P70478

MASS(Da):310533

GeneID:24205

Synonyms:Apc

Gene names:Apc

Standard solution:96ng/mL