RAN Antibody - Cat. #: CSB-PA019307ESR1HU

SKU: CSB-PA019307ESR1HU

Size :50ul

Clone Number:

Aliases:Androgen receptor associated protein 24 antibody; Androgen receptor-associated protein 24 antibody; ARA 24 antibody; ARA24 antibody; Gsp1 antibody; GTP binding nuclear protein RAN antibody; GTP-binding nuclear protein Ran antibody; GTPase Ran antibody; Guanosine triphosphatase Ran antibody; LPS antibody; OK/SW-cl.81 antibody; ran antibody; RAN member RAS oncogene family antibody; RAN_HUMAN antibody; RanGTPase antibody; Ras like protein TC4 antibody; Ras related nuclear protein antibody; Ras-like protein TC4 antibody; Ras-related nuclear protein antibody; RASL2 8 antibody; TC 4 antibody; TC4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P62826

Immunogen:Recombinant Human GTP-binding nuclear protein Ran protein (1-216AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background:GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAN

Research Areas:Others