RALA Antibody, FITC conjugated - Cat. #: CSB-PA019296LC01HU

SKU: CSB-PA019296LC01HU

Size :50ug

Clone Number:

Aliases:MGC48949 antibody; Ral a antibody; Ral A protein antibody; RAL antibody; RALA antibody; RALA_HUMAN antibody; Ras family small GTP binding protein RALA antibody; RAS like protein A antibody; Ras related protein RalA antibody; Ras-related protein Ral-A antibody; v ral simian leukemia viral oncogene homolog A (ras related) antibody; v ral simian leukemia viral oncogene homolog A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P11233

Immunogen:Recombinant Human Ras-related protein Ral-A protein (1-203AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RALA

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction