RAB8A Antibody - Cat. #: CSB-PA295669

SKU: CSB-PA295669

Size :50ul

Clone Number:

Aliases:AA409338 antibody; MEL antibody; Mel transforming oncogene (derived from cell line NK14) RAB8 homolog antibody; Mel transforming oncogene (derived from cell line NK14) antibody; Mel transforming oncogene (RAB8 homolog) antibody; Mel transforming oncogene antibody; MGC124948 antibody; Oncogene c mel antibody; Oncogene c-mel antibody; RAB8 antibody; RAB8A antibody; RAB8A member RAS oncogene family antibody; RAB8A_HUMAN antibody; Ras associated protein RAB8 antibody; Ras related protein Rab 8A antibody; Ras-related protein Rab-8A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P61006

Immunogen:Synthetic peptide of Human RAB8A

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAB8A

Research Areas:Signal transduction