Purified Anti-Mouse CD45 Antibody[M1/9.3.4.HL.3]

SKU: AN007700P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD45/PTPRC

Target Synonym:B220;CD45;CD45 antigen;CD45R;CD45R0;LCA;L-CA;LY5;protein tyrosine phosphatase;receptor type;Receptor-type tyrosine-protein phosphatase C;T200;Ly-5;Ptprc;c polypeptide;CD 45;GP180;homolog of;Leukocyte common antigen;loc;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;protein tyrosine phosphatase;receptor type;C;receptor type C;T200 glycoprotein;T200 leukocyte common antigen

Research Areas:

Conjugation:Unconjugated

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:

Isotype:Rat IgG2a, κ

Clonality:Monoclonal

Clone NO.:M1/9.3.4.HL.3

UNIProt ID:P06800

Background:CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse CD45/PTPRC protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:19264