Purified Anti-Mouse CD150 Antibody[TC15-12F12.2]

SKU: GBS-F1177A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD150

Target Synonym:SLAM family member;SLAMF;CD 150;CD150;CD150 antigen;Signaling lymphocytic activation molecule;SLAM family member 1;Slam;Slamf1; IPO-3

Research Areas:

Conjugation:Unconjugated

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:

Isotype:Rat IgG2a, λ

Clonality:Monoclonal

Clone NO.:TC15-12F12.2

UNIProt ID:Q9QUM4

Background:CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse CD150 protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:27218