Purified Anti-Mouse CD105 Antibody[MJ7/18]

SKU: GBS-F1233A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD105

Target Synonym:HHT;ORW1;AI528660;AI662476;CD105;END;Endo;Endoglin;HHT1;ORW;S-endoglin;Edg;Eng;END;HHT1;ORW;ORW1;CD 105;CD105 antigen;EGLN;FLJ41744;Osler Rendu Weber syndrome 1;RP11 228B15.2;SN6

Research Areas:

Conjugation:Unconjugated

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:

Isotype:Rat IgG2a, κ

Clonality:Monoclonal

Clone NO.:MJ7/18

UNIProt ID:Q63961

Background:Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD105 protein

Buffer:PBS, pH 7.2. Contains 0.05% Proclin300.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:13805