Purified Anti-Human CD27 Antibody[O323]

SKU: GBS-F11400P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD27

Target Synonym:S152. LPFS;T-cell activation antigen CD;TNFRSF;S152.LPFS;CD27;S152;S152. LPFS2;T14;TNFRSF7;Tp55;S152.LPFS2;CD27L receptor;T-cell activation antigen CD27; S152; TNFRSF7;CD 27;CD27 antigen;CD27 molecule;LPFS2;MGC20393;OTTHUMP00000238557;T cell activation antigen CD27;T cell antivation antigen S152;TNFRSF 7;TNFSF7;Tp 55;Tumor necrosis factor receptor superfamily member 7

Research Areas:Immunology;Cancer;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:O323

UNIProt ID:P26842

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD27 protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:939