PTPN6 Antibody - Cat. #: CSB-PA150036

SKU: CSB-PA150036

Size :50ul

Clone Number:

Aliases:70Z-SHP antibody; EC 3.1.3.48 antibody; HCP antibody; HCPH antibody; Hematopoietic cell phosphatase antibody; Hematopoietic cell protein tyrosine phosphatase antibody; Hematopoietic cell protein-tyrosine phosphatase antibody; HPTP1C antibody; Protein tyrosine phosphatase 1C antibody; Protein tyrosine phosphatase non receptor type 6 antibody; Protein tyrosine phosphatase SHP1 antibody; Protein-tyrosine phosphatase 1C antibody; protein-tyrosine phosphatase SHP 1 antibody; Protein-tyrosine phosphatase SHP-1 antibody; PTN6_HUMAN antibody; PTP 1C antibody; PTP-1C antibody; PTP1C antibody; Ptpn6 antibody; SH PTP 1 antibody; SH PTP1 antibody; SH-PTP1 antibody; SHP 1 antibody; SHP 1L antibody; SHP1 antibody; SHP1L antibody; tyrosine protein phosphatase non receptor type 6 antibody; Tyrosine-protein phosphatase non-receptor type 6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P29350

Immunogen:Fusion protein of Human PTPN6

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTPN6

Research Areas:Cancer;Cell biology?Developmental biology;Signal transduction