PTMA Antibody - Cat. #: CSB-PA799716

SKU: CSB-PA799716

Size :50ul

Clone Number:

Aliases:Prothymosin alpha (gene sequence 28) antibody; Prothymosin alpha antibody; Prothymosin alpha like 1 protein antibody; PTMA antibody; PTMA_HUMAN antibody; Thymalfasin antibody; Thymosin alpha 1 acetate antibody; Thymosin alpha 1 antibody; Thymosin alpha antibody; Thymosin alpha-1 antibody; TMSA antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P06454

Immunogen:Full length fusion protein

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTMA

Research Areas:Cell biology;Signal transduction