PTGES3 antibody , Cat. # FNab06918

SKU: FNab06918

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2(PGH2) to prostaglandin E2(PGE2)(PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes(PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway(PubMed:24711448).

Immunogen:prostaglandin E synthase 3(cytosolic)

Synonyms:P23, TEBP

Observed MW:21-23 kDa

Uniprot ID:Q15185

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IF, IP, WB, FC

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200

Gene ID:10728

Research Area:Signal Transduction