PTCH1 antibody , Cat. # FNab10084

SKU: FNab10084

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Immunogen:patched homolog 1

Synonyms:HPE7, NBCCS, Patched, patched homolog 1, Patched1, Protein patched homolog 1, PTC, PTC1, PTCH, PTCH1, PTCH11

Observed MW:161 kDa

Uniprot ID:Q13635

Reactivity:Human, Rat

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:5727

Research Area:Neuroscience, Cell Division and Proliferation