PSIP1 Monoclonal Antibody

SKU: BT-MCA2756

Size:100μL

Background:Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

Research_area:Epigenetics and nuclear signaling, Microbiology

Target_protein:PSIP1

applications:WB, IHC, ICC

Reactivity:Human, Monkey, Rat

Clonality:Monoclonal

Clone ID:6E4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PSIP1

Immunogen:Purified recombinant fragment of human PSIP1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):75kDa

UniProt accession:O75475

Synonyms:p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1

GeneID:11168