PRKACA Monoclonal Antibody

SKU: BT-MCA2772

Size:100μL

Background:cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Research_area:Others

Target_protein:PRKACA

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:7H3A4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PRKACA

Immunogen:Purified recombinant fragment of human PRKACA (AA: 1-120) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):40.6kDa

UniProt accession:P17612

Synonyms:PKACA

GeneID:5566