PRDM2 Rabbit Polyclonal Antibody

SKU: BT-AP12183

Size:100μL

Background:This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein| estrogen receptor| and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized| it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma| (2) act as a transcriptional activator of the heme-oxygenase-1 gene| and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Epigenetics and nuclear signaling

Target_protein:PRDM2

applications:WB

Reactivity:Human, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PRDM2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):188980

UniProt accession:Human: Q13029; Rat: Q63755

Synonyms:PRDM2

GeneID:Human: 7799; Rat: 313678