GeneBio Systems
PPM1B Polyclonal Antibody
PPM1B Polyclonal Antibody
SKU:E-AB-52842
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:PPM1B
Target Synonym:MGC21657;OTTHUMP00000158953;OTTHUMP00000158954;OTTHUMP00000158955;OTTHUMP00000202394;OTTHUMP00000202395;OTTHUMP00000202399;PP2C beta;PP2C beta X;PP2C-beta;PP2CB;PP2Cbeta;PPC2BETAX;PPM 1B;Ppm1b;PPM1B;Protein phosphatase 1B (formerly 2C) magnesium dependent beta isoform;Protein phosphatase 1B;Protein phosphatase 1B magnesium dependent beta isoform;Protein phosphatase 2C beta isoform;Protein phosphatase 2C isoform beta;Protein phosphatase 2C like protein;Protein phosphatase; Mg2+/Mn2+ dependent; 1B
Research Areas:Cancer;Cell Biology;Signal transduction
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human
Application:IHC
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:O75688
Accession:
Background:The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Concentration:1.44 mg/mL
Immunogen:Fusion protein of human PPM1B
Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method:Antigen affinity purification
Dilution:IHC 1:50-1:300
Calculated MW:
ObservedMW:
