PPBP Polyclonal Antibody

SKU: E-AB-19288

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PPBP

Target Synonym: B TG1;Beta TG;Beta thromboglobulin;Beta-TG;C-X-C motif chemokine 7;Chemokine (C X C motif) ligand 7;Connective tissue activating peptide III;CTAP 3;CTAP III;CTAP-III;CTAP-III(1-81);CTAP3;CTAPIII;CXC chemokine ligand 7;CXCL 7;CXCL7;CXCL7;LA PF 4;LA-PF4;LDGF;Leukocyte derived growth factor;Leukocyte-derived growth factor;Low-affinity platelet factor IV;Macrophage-derived growth factor;MDGF;NAP 2;NAP-2;NAP-2(1-63);NAP-2(1-66);NAP-2(73);NAP-2(74);Neutrophil activating peptide 2;Neutrophil-activating peptide 2(1-63);PBP;Platelet basic protein;PPBP;Pro platelet basic protein (chemokine (C-X-C motif) ligand 7);Pro platelet basic protein;SCYB7;Small inducible cytokine subfamily B member 7;Small-inducible cytokine B7;TC1;TC2;TGB;TGB1;THBGB;THBGB1;Thrombocidin 1;Thrombocidin 2;Thromboglobulin;beta-1

Research Areas: Cardiovascular;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P02775

Accession:

Background: PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Colloid Adenoma. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. GO annotations related to this gene include growth factor activity and glucose transmembrane transporter activity. An important paralog of this gene is CXCL1. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

Concentration: 0.8 mg/mL

Immunogen: Synthetic peptide of human PPBP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:25-1:100

Calculated MW: 14 kDa

ObservedMW: Refer to figures