PON3/paraoxonase 3 Polyclonal Antibody

SKU: E-AB-40576

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PON3

Target Synonym: Serum paraoxonase/lactonase 3; PON3

Research Areas: Neuroscience;Cardiovascular;Signal Transduction;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q15166

Accession:

Background: The paraoxonase (PON) gene family of antioxidant enzymes includes three known members located adjacent to each other on chromosome 7. Paraoxonase/lactonase 3 (PON3) is a 354 amino acid, 39.6 kDa protein that is secreted into the bloodstream and associates with high-density lipoprotein (HDL). PON3 has lactonase activity (EC 3.1.1) and rapidly hydrolyzes lactones. PON3 exhibits no paraoxonase and very limited arylesterase activities. PON3 is an important antioxidant and can inhibit the oxidation of low-density lipoprotein (LDL), a function that may slow the initiation and progression of atherosclerosis.

Concentration: 1 mg/mL

Immunogen: Recombinant Human PON3 protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:1000-2000

Calculated MW: 39kDa

ObservedMW: 40kDa