POLR2E Antibody, Biotin conjugated - Cat. #: CSB-PA018332LD01HU

SKU: CSB-PA018332LD01HU

Size :50ug

Clone Number:

Aliases:and III subunit ABC1 antibody; and III subunit RPABC1 antibody; DNA directed RNA polymerase II 23 kda polypeptide antibody; DNA directed RNA polymerase II 23 kDa polypeptide antibody; DNA directed RNA polymerase II polypeptide E antibody; DNA directed RNA polymerase II subunit E antibody; DNA directed RNA polymerases I II and III subunit RPABC1 antibody; DNA-directed RNA polymerase II 23 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit E antibody; DNA-directed RNA polymerases I antibody; hRPB25 antibody; hsRPB5 antibody; II antibody; Polr2e antibody; Polymerase (RNA) II (DNA directed) polypeptide E (25kD) antibody; Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa antibody; RNA polymerases I antibody; RNA polymerases I, II, and III subunit ABC1 antibody; RPAB1_HUMAN antibody; RPABC1 antibody; RPB5 antibody; RPB5 homolog antibody; XAP4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P19388

Immunogen:Recombinant Human DNA-directed RNA polymerases I, II, and III subunit RPABC1 protein (1-210AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:POLR2E

Research Areas:Epigenetics and Nuclear Signaling