POLR1B Antibody - Cat. #: CSB-PA799360

SKU: CSB-PA799360

Size :100ul

Clone Number:

Aliases:A127 antibody; DNA directed RNA polymerase I 135kDa polypeptide antibody; DNA directed RNA polymerase I antibody; DNA directed RNA polymerase I subunit RPA2 antibody; DNA-directed RNA polymerase I 135 kDa polypeptide antibody; DNA-directed RNA polymerase I subunit rpa2 antibody; FLJ10816 antibody; FLJ21921 antibody; MGC131780 antibody; OTTHUMP00000161989 antibody; OTTHUMP00000203643 antibody; OTTHUMP00000203645 antibody; POLR 1B antibody; polr1b antibody; Polymerase (RNA) I polypeptide B 128kDa antibody; Polymerase (RNA) I polypeptide B antibody; RNA polymerase I polypeptide B antibody; RNA polymerase I subunit 2 antibody; RPA 135 antibody; RPA116 antibody; RPA135 antibody; RPA2 antibody; RPA2_HUMAN antibody; Rpo1 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H9Y6

Immunogen:Synthesized peptide derived from C-terminal of Human POLR1B.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft By similarity.

Ota T., Nat. Genet. 36:40-45(2004).
Hillier L.W., Nature 434:724-731(2005).
Miller G., EMBO J. 20:1373-1382(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:POLR1B

Research Areas:Epigenetics and Nuclear Signaling