PODXL Monoclonal Antibody

SKU: BT-MCA4326

Size:100μL

Background:This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Research_area:Signal transduction, Cardiovascular, Cancer, Stem cells

Target_protein:PODXL

applications:IHC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:2H2G2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PODXL

Immunogen:Purified recombinant fragment of human PODXL (AA: Extra(23-172)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):58.6kda

UniProt accession:O00592

Synonyms:PC, PDX, PCLP, Gp200, gp135, PCLP-1, PODXL1

GeneID:5420