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Gene Bio Systems

PMAIP1 Antibody - Cat. #: CSB-PA969433

PMAIP1 Antibody - Cat. #: CSB-PA969433

SKU:CSB-PA969433

Regular price $867.34 CAD
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Size :100ul

Clone Number:

Aliases:Adult T cell leukemia derived PMA responsive antibody; APR antibody; APR_HUMAN antibody; ATL-derived antibody; Immediate early response protein APR antibody; Immediate-early-response protein APR antibody; NOXA antibody; Phorbol 12 myristate 13 acetate induced protein 1 antibody; Phorbol-12-myristate-13-acetate-induced protein 1 antibody; PMA induced protein 1 antibody; PMA-induced protein 1 antibody; PMA-responsive gene antibody; Pmaip1 antibody; Protein Noxa antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13794

Immunogen:Full length fusion protein

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1?By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.?

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PMAIP1

Research Areas:Cancer;Cell biology;Metabolism

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