PLXNB2 Antibody? Biotin conjugated - Cat. #: CSB-PA018223LD01HU

SKU: CSB-PA018223LD01HU

Size :50ul

Clone Number:

Aliases:PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15031

Immunogen:Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \'Tyr-1248\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Antigen Affinity purified & Affinity purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLXNB2

Research Areas:Others