PLUNC rabbit pAb

SKU: ES6514

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from the Internal region of human PLUNC.

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:51297

Human_swiss_prot_no:Q9NP55

Subcellular_location:Secreted . Apical side of airway epithelial cells. Detected in airway surface liquid, nasal mucus and sputum.

Other_name:BPIFA1; LUNX; NASG; PLUNC; SPURT; BPI fold-containing family A member 1; Lung-specific protein X; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; Secretory protein in upper respiratory tracts; Trach

Background:This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014],