PLG Antibody - Cat. #: CSB-PA970985

SKU: CSB-PA970985

Size :100ul

Clone Number:

Aliases:Plasmin antibody; Plasmin heavy chain A antibody; Plasmin light chain B antibody; Plasminogen antibody; PLG antibody; PLMN_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P00747

Immunogen:Synthesized peptide derived from N-terminal of Human PLG.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.

Petersen T.E., J. Biol. Chem. 265:6104-6111(1990).
Forsgren M., FEBS Lett. 213:254-260(1987).
Browne M.J., Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLG

Research Areas:Cancer?Cardiovascular?Cell biology