PLCZ1 Antibody, FITC conjugated - Cat. #: CSB-PA768240LC01HU

SKU: CSB-PA768240LC01HU

Size :50ug

Clone Number:

Aliases:1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase zeta 1 antibody; 1-phosphatidylinositol-4 antibody; 5-bisphosphate phosphodiesterase zeta-1 antibody; MGC149685 antibody; NYD SP27 antibody; Phosphoinositide phospholipase C zeta 1 antibody; Phosphoinositide phospholipase C-zeta-1 antibody; Phospholipase C zeta 1 antibody; Phospholipase C-zeta-1 antibody; PI phospholipase C zeta 1 antibody; PLC zeta 1 antibody; PLC-zeta-1 antibody; PLCZ1 antibody; PLCZ1_HUMAN antibody; PLCzeta antibody; Testis development protein NYD SP27 antibody; Testis development related NYD SP27 antibody; Testis-development protein NYD-SP27 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86YW0

Immunogen:Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 protein (1-415AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLCZ1

Research Areas:Cancer; Metabolism