PLAUR Polyclonal Antibody

SKU: E-AB-10547

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PLAUR

Target Synonym:CD 87;CD87;CD87 antigen;MO 3;MO3;Monocyte activation antigen Mo3;Plasminogen activator receptor urokinase;Plasminogen activator urokinase receptor;PLAUR;U PAR;u plasminogen activator receptor;U-PAR;u-plasminogen activator receptor form 2;UPA receptor;uPAR;UPAR;Urinary plasminogen activator receptor;URKR;Urokinase plasminogen activator receptor;Urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor

Research Areas:Cancer;Cardiovascular;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q03405

Accession:

Background:This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Concentration:0.4 mg/mL

Immunogen:Recombinant protein of human PLAUR

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:37kDa

ObservedMW: