PLAT Polyclonal Antibody

SKU: E-AB-12879

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PLAT

Target Synonym:Alteplase;DKFZp686I03148;Plasminogen activator tissue;Plasminogen activator tissue type;PLAT;Reteplase;t PA;T Plasminogen Activator;t-PA;T-plasminogen activator;Tissue plasminogen activator (t PA);Tissue type plasminogen activator;Tissue-type plasminogen activator chain B;tPA;TPA;TPA1

Research Areas:Cancer;Cell Biology;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P00750

Accession:

Background:This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Concentration:0.4 mg/mL

Immunogen:Synthetic peptide of human PLAT

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:200-1:1000;IHC 1:50-1:200

Calculated MW:63kDa

ObservedMW: