PKR1 rabbit pAb

SKU: ES3231

Size: 100μL

Source:Rabbit

Applications:WB; IF;ELISA;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000;IHC-p 1:100-500

Immunogen:The antiserum was produced against synthesized peptide derived from human PKR1. AA range:19-68

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):45kD

Human_gene_id:10887

Human_swiss_prot_no:Q8TCW9

Subcellular_location:Cell membrane; Multi-pass membrane protein.

Other_name:PROKR1; GPR73; PKR1; Prokineticin receptor 1; PK-R1; G-protein coupled receptor 73; G-protein coupled receptor ZAQ; GPR73a

Background:prokineticin receptor 1(PROKR1) Homo sapiens This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016],