PKM2 Polyclonal Antibody

SKU: D-AB-10309L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PKM2

Target Synonym:Pyruvate kinase PKM;Cytosolic thyroid hormone-binding protein;Opa-interacting protein 3;Pyruvate kinase 2/3;Pyruvate kinase muscle isozyme;Threonine-protein kinase PKM2;Thyroid hormone-binding protein 1 (THBP1);PKM;OIP3;PK2;PK3;PKM2

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P14618

Accession:

Background:This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP,generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein,a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells,suggesting a role of this protein in bacterial pathogenesis.

Concentration:1 mg/mL

Immunogen:Recombinant Human PKM2 Protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000

Calculated MW:58kDa

ObservedMW:60 kDa