PIM2 Antibody - Cat. #: CSB-PA438428

SKU: CSB-PA438428

Size :50ul

Clone Number:

Aliases:OTTHUMP00000025825 antibody; Pim 2 oncogene antibody; Pim 2h antibody; Pim-2h antibody; PIM2 antibody; PIM2 Oncogene antibody; PIM2_HUMAN antibody; Pim2h antibody; Proto Oncogene PIM2 antibody; Proto-oncogene Pim-2 (serine threonine kinase) antibody; Serine/threonine kinase PIM2 antibody; Serine/threonine-protein kinase Pim-2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9P1W9

Immunogen:Fusion protein of Human PIM2

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PIM2

Research Areas:Cancer;Signal transduction