PIK3CG Monoclonal Antibody

SKU: BT-MCA2442

Size:100μL

Background:This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Research_area:Signal Transduction

Target_protein:PIK3CG

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:4B5D2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PIK3CG

Immunogen:Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):126.5kDa

UniProt accession:P48736

Synonyms:PI3K, PIK3, PI3CG, PI3Kgamma, p110gamma, p120-PI3K

GeneID:5294