PIDD1 Monoclonal Antibody

SKU: BT-MCA4604

Size:100μL

Background:The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Research_area:Others

Target_protein:PIDD1

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:3C5G8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PIDD1

Immunogen:Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):99.7kDa

UniProt accession:Q9HB75

Synonyms:LRDD, PIDD

GeneID:55367