Phospho-PRKAB1 (Ser181) Antibody - Cat. #: CSB-PA165739

SKU: CSB-PA165739

Size :100ul

Clone Number:

Aliases:1300015D22Rik antibody; 5''-AMP-activated protein kinase subunit beta-1 antibody; 5'-AMP-activated protein kinase beta-1 subunit antibody; AAKB1_HUMAN antibody; AMP-activated protein kinase beta subunit antibody; AMP-ACTIVATED PROTEIN KINASE; NONCATALYTIC; BETA-1 antibody; AMP-activated; noncatalytic; beta-1 antibody; AMPK antibody; AMPK beta 1 chain antibody; AMPK subunit beta-1 antibody; AMPK-BETA-1 antibody; AMPKb antibody; AU021155 antibody; E430008F22 antibody; HAMPKb antibody; MGC17785 antibody; PRKAB1 antibody; Protein kinase AMP activated non catalytic subunit beta 1 antibody; protein kinase; AMP-activated; beta 1 non-catalytic subunit antibody; protein kinase; AMP-activated; noncatalytic; beta-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y478

Immunogen:Peptide sequence around phosphorylation site of Serine 181(L-S-S(p)-S-P) derived from Human AMPK ?1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PRKAB1

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction