Phospho-PLD2 (Tyr169) Antibody - Cat. #: CSB-PA983138

SKU: CSB-PA983138

Size :100ul

Clone Number:

Aliases:Choline phosphatase 2 antibody; EC 3.1.4.4 antibody; hPLD 2 antibody; hPLD2 antibody; mPLD2 antibody; Phosphatidylcholine hydrolyzing phospholipase D2 antibody; Phosphatidylcholine-hydrolyzing phospholipase D2 antibody; Phospholipase D2 antibody; PhospholipaseD2 antibody; PLD 2 antibody; PLD1C antibody; Pld2 antibody; PLD2_HUMAN antibody; Pldc antibody; rPLD2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14939

Immunogen:Peptide sequence around phosphorylation site of tyrosine 169(E-N-Y(p)-L-N) derived from Human PLD2.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100

Background:

Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.

Steed P.M., FASEB J. 12:1309-1317(1998).
Lopez I., J. Biol. Chem. 273:12846-12852(1998).
Divecha N., EMBO J. 19:5440-5449(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLD2

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction