Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody

SKU: E-AB-21027

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: p38 (phospho Thr180/Tyr182)

Target Synonym: CSAID Binding Protein 1;CSAID binding protein;CSAID-binding protein;Csaids binding protein;CSBP 1;CSBP 2;CSBP;CSBP1;CSBP2;CSPB1;Cytokine suppressive anti-inflammatory drug-binding protein;EXIP;MAP kinase 14;MAP kinase MXI2;MAP kinase p38 alpha;MAPK 14;MAPK14;MAX interacting protein 2;MAX-interacting protein 2;Mitogen Activated Protein Kinase 14;Mitogen activated protein kinase p38 alpha;Mitogen-activated protein kinase 14;Mitogen-activated protein kinase p38 alpha;MK14;Mxi 2;MXI2;p38 ALPHA;p38;p38 MAP kinase;p38 MAPK;p38 mitogen activated protein kinase;p38ALPHA;p38alpha Exip;PRKM14;PRKM15;RK;SAPK2A

Research Areas: Cancer;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q16539

Accession:

Background: MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human p38 around the phosphorylation site of Thr180/Tyr182

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:50-1:200

Calculated MW: 41kDa

ObservedMW: 38kDa