Phospho-NR4A1 (Ser351) Antibody - Cat. #: CSB-PA198130

SKU: CSB-PA198130

Size :100ul

Clone Number:

Aliases:Early response protein NAK1 antibody; GFRP 1 antibody; GFRP antibody; GFRP1 antibody; Growth factor inducible nuclear protein N10 antibody; Growth Factor Inducible Nuclear Protein NP10 antibody; Growth Factor Response Protein 1 antibody; Hbr1 antibody; HMR antibody; Hormone Receptor antibody; MGC9485 antibody; N10 antibody; N10 nuclear protein antibody; NAK 1 antibody; NAK1 antibody; Nerve growth factor IB nuclear receptor variant 1 antibody; NGFIB antibody; NP 10 antibody; NP10 antibody; NR4A1 antibody; NR4A1_HUMAN antibody; Nuclear hormone receptor NUR/77 antibody; Nuclear Hormone Receptor TR3 antibody; Nuclear receptor subfamily 4 group A member 1 antibody; NUR77 antibody; NUR77; mouse; homolog of antibody; Orphan nuclear receptor HMR antibody; Orphan nuclear receptor NR4A1 antibody; Orphan nuclear receptor TR3 antibody; Orphan receptor tr3 antibody; Receptor NGFIB antibody; ST 59 antibody; ST-59 antibody; ST59 antibody; Steroid receptor TR3 antibody; Testicular receptor 3 antibody; TR 3 antibody; TR3 antibody; TR3 orphan receptor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P22736

Immunogen:Peptide sequence around phosphorylation site of Serine351(L-P-S(p)-K-P) derived from Human Nuclear Receptor NR4A1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

Nakai A., Mol. Endocrinol. 4:1438-1443(1990).
Chang C., J. Steroid Biochem. 34:391-395(1989).
Bondy G.P., Cell Growth Differ. 2:203-208(1991)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NR4A1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology