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GeneBio Systems

Phospho-FOXO1/3 (Ser322/S325) Polyclonal Antibody

Phospho-FOXO1/3 (Ser322/S325) Polyclonal Antibody

SKU:E-AB-21016

Regular price $718.20 CAD
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: FoxO1/3 (phospho Ser322/S325)

Target Synonym: FOXO1;FKHR;FOXO1A;Forkhead box protein O1;Forkhead box protein O1A;Forkhead in rhabdomyosarcoma;FOXO3;FKHRL1;FOXO3A;Forkhead box protein O3;AF6q21 protein;Forkhead in rhabdomyosarcoma-like 1

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Metabolism;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q12778,O43524

Accession:

Background: FOXO1 (Forkhead Box O1) is a Protein Coding gene. Diseases associated with FOXO1 include Rhabdomyosarcoma 2, Alveolar and Rhabdomyosarcoma. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is FOXO3. FOXO3 (Forkhead Box O3) is a Protein Coding gene. Diseases associated with FOXO3 include Rhabdomyosarcoma and Lung Cancer. Among its related pathways are Development IGF-1 receptor signaling and Constitutive Signaling by AKT1 E17K in Cancer. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein kinase binding. An important paralog of this gene is FOXO1.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human FoxO1/3 around the phosphorylation site of Ser322/S325

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW: 70kDa

ObservedMW: 97kDa

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