Phospho-EPB41 (Tyr660/418) Antibody - Cat. #: CSB-PA242308

SKU: CSB-PA242308

Size :100ul

Clone Number:

Aliases:4.1R antibody; 41_HUMAN antibody; Band 4.1 antibody; E41P antibody; EL 1 antibody; EL1 antibody; EL1 gene antibody; Elliptocytosis 1 antibody; Elliptocytosis 1 RH linked antibody; EPB 4.1 antibody; EPB 41 antibody; EPB4.1 antibody; Epb41 antibody; Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked) antibody; Erythrocyte membrane protein band 4.1 antibody; Erythrocyte surface protein band 4.1 antibody; HE antibody; P4.1 antibody; Protein 4.1 antibody; Protein 4.1; red blood cell type antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P11171

Immunogen:Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986).
Tang T.K., Adv. Exp. Med. Biol. 241:81-95(1988).
Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717(1988).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EPB41

Research Areas:Cardiovascular;Signal transduction