PGP9.5 Rabbit pAb(UCHL-1)

SKU: ES20648

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human; Mouse; Rat

Dilution:IHC-p 1:50-200, WB 1:500-2000

Immunogen:Recombinant Protein derived from human PGP9.5

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):25kD

Human_gene_id:7345

Human_swiss_prot_no:P09936

Subcellular_location:Cytoplasm . Endoplasmic reticulum membrane ; Lipid-anchor . About 30% of total UCHL1 is associated with membranes in brain.

Other_name:Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (EC 6.-.-.-) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)

Background:The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009],