PGFRA Polyclonal Antibody

SKU: AN006950L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PGFRA

Target Synonym:GAS;PDGFRA;CD140A;PDGFR-2;PDGFR2;GAS9;RHEPDGFRA;PDGF-RαAlpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD_antigen: CD140a;CD140 antigen-like family member A;CD140a antigen;MGC74795;PDGF alpha chain;PDGFR 2;PDGFR alpha;PDGFRA/BCR fusion;PDGFR-alpha;PDGF-R-alpha;PGFRA;Platelet derived growth factor receptor;Platelet derived growth factor receptor 2;Platelet derived growth factor receptor alpha;Platelet derived growth factor receptor alpha polypeptide;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2;platelet-derived growth factor receptor A;Platelet-derived growth factor receptor alpha;platelet-derived growth factor receptor α;Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein

Research Areas:Cardiovascular;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P16234

Accession:

Background:This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Concentration:1 mg/mL

Immunogen:Recombinant Human PGFRA protein expressed by E.coli

Buffer:PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000

Calculated MW:123 kDa

ObservedMW:150 kDa