Per2(Phospho Ser662) Polyclonal Antibody

SKU: BT-AP12937

Size:100μL

Background:This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

Research_area:Cardiovascular; Epigenetics and nuclear signaling; Metabolism; Neuroscience; Signal transduction

Target_protein:PER2

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Period circadian protein homolog 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):136579

UniProt accession:Human: O15055; Mouse: O54943

Synonyms:Period circadian protein homolog 2; PER2; KIAA0347; Period circadian protein homolog 2; hPER2; Circadian clock protein PERIOD 2

GeneID:Human: 8864; Mouse: 18627