PE Anti-Mouse FcεRIα Antibody(MAR-1)

SKU: PE-30221

Size: 50T

Target: Mouse FcεRIα

Form: liquid

Conjugation: PE

Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).

Purification: 0

Purity: 0

Host: Armenian Hamster

Clonality: Monoclonal

Clone ID: MAR-1

Isotype: IgG

Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Immunogen: 0

Synonyms: Fc-epsilon RI-alpha|FcERI|Fcer1a|High affinity immunoglobulin epsilon receptor subunit alpha

Observed MW:

Uniprot ID: P20489

Reactivity: Mouse

Tested Application: FC

Recommended dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

image5:

Gene ID: 14125

Research Area:

Catagory: Flow cytometry Antibodies