PDE6G Rabbit pAb

SKU: ES14185

Size: 100μL

Source:Rabbit

Applications:IHC; ELISA

Reactivity:Human; Mouse

Dilution:IHC-p 1:50-200, ELISA(peptide)1:5000-20000

Immunogen:Synthesized peptide derived from human PDE6G AA range: 10-90

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:5148

Human_swiss_prot_no:P18545

Subcellular_location:plasma membrane,photoreceptor disc membrane,

Other_name:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)

Background:This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],