PAX6 Rabbit Polyclonal Antibody

SKU: BT-AP11794

Size:100μL

Background:This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues| particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

Research_area:Developmental biology; Epigenetics and nuclear signaling; Neuroscience; Stem cells

Target_protein:PAX6

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PAX6

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):46420

UniProt accession:Human: P26367; Mouse: P63015; Rat: P63016

Synonyms:PAX6; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin

GeneID:Human: 5080; Mouse: 18508; Rat: 25509