PAK alpha(Phospho Ser199) Polyclonal Antibody

SKU: BT-AP12746

Size:100μL

Background:This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Cell biology; Signal transduction

Target_protein:PAK1

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Serine/threonine-protein kinase PAK 1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):60647

UniProt accession:Human: Q13153; Mouse: O88643; Rat: P35465

Synonyms:Serine/threonine-protein kinase PAK 1; PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK

GeneID:Human: 5058; Rat: 29431