P62/SQSTM1 antibody , Cat. # FNab06087

SKU: FNab06087

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Immunogen:sequestosome 1

Synonyms:P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62

Observed MW:62 kDa

Uniprot ID:Q13501

Reactivity:Human

Tested Application:ELISA, WB, IHC, IF, IP

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50

Gene ID:8878

Research Area:Neuroscience, Cardiovascular, Metabolism, Signal Transduction