OPTN Antibody - Cat. #: CSB-PA924414

SKU: CSB-PA924414

Size :50ul

Clone Number:

Aliases:14.7K interacting protein antibody; Ag9 C5 antibody; ALS12 antibody; E3 14.7K interacting protein antibody; E3-14.7K-interacting protein antibody; FIP 2 antibody; FIP-2 antibody; FIP2 antibody; Glaucoma 1 open angle E (adult onset) antibody; Glaucoma 1 open angle E antibody; GLC1E antibody; HIP 7 antibody; HIP-7 antibody; HIP7 antibody; Huntingtin interacting protein 7 antibody; Huntingtin interacting protein HYPL antibody; Huntingtin interacting protein L antibody; Huntingtin yeast partner L antibody; Huntingtin-interacting protein 7 antibody; Huntingtin-interacting protein L antibody; HYPL antibody; Injury inducible protein I 55 antibody; NEMO related protein antibody; NEMO-related protein antibody; NRP antibody; Optic neuropathy inducing protein antibody; Optic neuropathy-inducing protein antibody; Optineurin antibody; OPTN antibody; OPTN_HUMAN antibody; TFIIIA IntP antibody; TFIIIA-IntP antibody; Transcription factor IIIA interacting protein antibody; Transcription factor IIIA-interacting protein antibody; Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96CV9

Immunogen:Fusion protein of Human OPTN

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OPTN

Research Areas:Neuroscience;Immunology;Signal transduction