OGFR rabbit pAb

SKU: ES4587

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human OGFR. AA range:138-187

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):90kD

Human_gene_id:11054

Human_swiss_prot_no:Q9NZT2

Subcellular_location:Cytoplasm . Nucleus . The OGF/OGFR complex is probably translocated to the nucleus.

Other_name:OGFR; Opioid growth factor receptor; OGFr; Protein 7-60; Zeta-type opioid receptor

Background:The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008],