OCLN rabbit pAb

SKU: ES11811

Size: 100μL

Source:Rabbit

Applications:WB IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

Immunogen:Synthesized peptide derived from part region of human protein. AA350-400

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):57kD

Human_gene_id:100506658

Human_swiss_prot_no:Q16625

Subcellular_location:Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction .

Other_name:

Background:This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],